UK:*UK and possibly other pronunciationsUK and possibly other pronunciations/ˈpeɪnkɪlər/US:USA pronunciation: IPA and respellingUSA pronuncation: IPA/ˈpeɪnˌkɪlɚ/ ,USA pronunciation: respelling(pānkil′ər)

WordReference Random House Learner's Dictionary of American English © 2020
pain•kill•er /ˈpeɪnˌkɪlɚ/USA pronunciation   n. [countable]
  1. Drugssomething, as a drug or treatment, that relieves pain:Some narcotic drugs are painkillers.
pain•kill•ing, adj. 

WordReference Random House Unabridged Dictionary of American English © 2020
pain•kill•er  (pānkil′ər),USA pronunciation n. 
  • Drugsa drug, treatment, or anything else that relieves pain, esp. an analgesic.
  • [1850–55, Amer.;
    pain + killer]
    painkill′ing, adj. 

    Collins Concise English Dictionary © HarperCollins Publishers::
    painkiller /ˈpeɪnˌkɪlə/ n
    1. an analgesic drug or agent
    2. anything that relieves pain
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